Improved Neural Processing Efficiency in a Chronic Aphasia Patient Following Melodic Intonation Therapy: A Neuropsychological and Functional MRI Study
نویسندگان
چکیده
Melodic intonation therapy (MIT) is a treatment program for the rehabilitation of aphasic patients with speech production disorders. We report a case of severe chronic non-fluent aphasia unresponsive to several years of conventional therapy that showed a marked improvement following intensive 9-day training on the Japanese version of MIT (MIT-J). The purpose of this study was to verify the efficacy of MIT-J by functional assessment and examine associated changes in neural processing by functional magnetic resonance imaging. MIT improved language output and auditory comprehension, and decreased the response time for picture naming. Following MIT-J, an area of the right hemisphere was less activated on correct naming trials than compared with before training but similarly activated on incorrect trials. These results suggest that the aphasic symptoms of our patient were improved by increased neural processing efficiency and a concomitant decrease in cognitive load.
منابع مشابه
Melodic Intonation Therapy in Chronic Aphasia: Evidence from a Pilot Randomized Controlled Trial
Melodic Intonation Therapy (MIT) is a language production therapy for severely non-fluent aphasic patients using melodic intoning and rhythm to restore language. Although many studies have reported its beneficial effects on language production, randomized controlled trials (RCT) examining the efficacy of MIT are rare. In an earlier publication, we presented the results of an RCT on MIT in subac...
متن کاملAnnals of the New York Academy of Sciences
Using an adapted version of Melodic Intonation Therapy (MIT), we treated an adolescent girl with a very large lefthemisphere lesion and severe nonfluent aphasia secondary to an ischemic stroke. At the time of her initial assessment 15 months after her stroke, she had reached a plateau in her recovery despite intense and long-term traditional speech-language therapy (approximately five times per...
متن کاملAugmenting melodic intonation therapy with non-invasive brain stimulation to treat impaired left-hemisphere function: two case studies
The purpose of this study was to investigate whether or not the right hemisphere can be engaged using Melodic Intonation Therapy (MIT) and excitatory repetitive transcranial magnetic stimulation (rTMS) to improve language function in people with aphasia. The two participants in this study (GOE and AMC) have chronic non-fluent aphasia. A functional Magnetic Resonance Imaging (fMRI) task was used...
متن کاملMelodic Intonation Therapy in subacute aphasia
Introduction Melodic Intonation Therapy (MIT) 1 is based on the observation that persons with severe nonfluent aphasia are often able to sing words or even short phrases they cannot produce during speech. MIT uses the melodic elements of speech, such as intonation and rhythm, to facilitate and improve language production. Although clinicians disagree about the usefulness of MIT, it has been tra...
متن کاملInsight into the neurophysiological processes of melodically intoned language with functional MRI
BACKGROUND Melodic Intonation Therapy (MIT) uses the melodic elements of speech to improve language production in severe nonfluent aphasia. A crucial element of MIT is the melodically intoned auditory input: the patient listens to the therapist singing a target utterance. Such input of melodically intoned language facilitates production, whereas auditory input of spoken language does not. MET...
متن کامل